Search Ontology:
ChEBI
roxadustat
- Term ID
- CHEBI:132774
- Synonyms
-
- ASP1517
- FG 4592
- FG-4592
- FG4592
- HIF prolyl-hydroxylase inhibitor
- N-[(4-hydroxy-1-methyl-7-phenoxyisoquinolin-3-yl)carbonyl]glycine
- roxadustat
- roxadustatum
- Definition
- An N-acylglycine resulting from the formal condensation of the amino group of glycine with the carboxy group of 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylic acid. It is an inhibitor of hypoxia inducible factor prolyl hydroxylase (HIF-PH).
- References
-
- CAS:808118-40-3
- KEGG:D10593
- PMID:26238121
- PMID:26494833
- PMID:26707978
- PMID:26808067
- PMID:26846333
- PMID:26947173
- PMID:27021233
- PMID:27082295
- PMID:27091985
- PMID:27094610
- PMID:27352308
- Reaxys:23352808
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from roxadustat
Phenotype where environments contain roxadustat
Phenotype modified by environments containing roxadustat
Human Disease Model