Search Ontology:
ChEBI
roxadustat
- Term ID
- CHEBI:132774
- Synonyms
-
- FG 4592
- FG-4592
- FG4592
- N-[(4-hydroxy-1-methyl-7-phenoxyisoquinolin-3-yl)carbonyl]glycine
- roxadustat
- roxadustatum
- Definition
- An N-acylglycine resulting from the formal condensation of the amino group of glycine with the carboxy group of 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylic acid. It is an inhibitor of hypoxia inducible factor prolyl hydroxylase (HIF-PH).
- References
-
- cas:808118-40-3
- kegg.drug:D10593
- pubmed:26238121
- pubmed:26494833
- pubmed:26707978
- pubmed:26808067
- pubmed:26846333
- pubmed:26947173
- pubmed:27021233
- pubmed:27082295
- pubmed:27091985
- pubmed:27094610
- pubmed:27352308
- reaxys:23352808
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from roxadustat
Phenotype where environments contain roxadustat
Phenotype modified by environments containing roxadustat
Phenotype affecting roxadustat
Human Disease Model