PHA-533533

Term ID

CHEBI:132239

Synonyms

(2S)-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-[4-(2-oxopyrrolidin-1-yl)phenyl]propanamide
PHA 533533
PHA533533

Definition

A carboxamide resulting from the formal condensation of the primary amino group of 5-cyclopropyl-1H-pyrazol-3-amine with the carboxy group of (2S)-2-phenylpropanoic acid in which the phenyl ring is substituted at the para position by a 2-oxopyrrolidin-1-yl group. A CDK2 inhibitor with antineoplastic activity.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: cyclopropanes pyrazoles pyrrolidin-2-ones secondary carboxamide tertiary carboxamide

cyclopropanes pyrazoles pyrrolidin-2-ones secondary carboxamide tertiary carboxamide Show first 5 Terms
has_role: antineoplastic agent EC 2.7.11.22 (cyclin-dependent kinase) inhibitor

antineoplastic agent EC 2.7.11.22 (cyclin-dependent kinase) inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from PHA-533533

Phenotype where environments contain PHA-533533

Phenotype modified by environments containing PHA-533533

Human Disease / Model Data

Citations