Search Ontology:
ChEBI

entinostat

Term ID
CHEBI:132082
Synonyms
  • BAY 86-5274
  • BAY86-5274
  • entinostat
  • entinostatum
  • MS 27-275
  • MS 275
  • MS-27-275
  • MS-275
  • N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide
  • N-[[4-[(2-aminoanilino)-oxomethyl]phenyl]methyl]carbamic acid 3-pyridinylmethyl ester
  • pyridin-3-ylmethyl {4-[(2-aminophenyl)carbamoyl]benzyl}carbamate
  • SNDX 275
  • SNDX-275
Definition
A member of the class of benzamides resulting from the formal condensation of the carboxy group of the pyridin-3-ylmethyl carbamate derivative of p-(aminomethyl)benzoic acid with one of the amino groups of benzene-1,2-diamine. It is an inhibitor of histone deacetylase isoform 1 (HDAC1) and isoform 3 (HDAC3).
References
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from entinostat
Phenotype where environments contain entinostat
Phenotype modified by environments containing entinostat
Phenotype affecting entinostat
Human Disease Model
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