meldonium

Term ID

CHEBI:131843

Synonyms

2-(2-carboxyethyl)-1,1,1-trimethyldiazanium
3-(2,2,2-trimethyldiazan-2-ium-1-yl)propanoate
3-(2,2,2-Trimethyldiazaniumyl)propanoate
3-(2,2,2-Trimethylhydrazine)propionate
meldonium
mildronate

Definition

An ammonium betaine that is β-alaninate in which one of the amino hydrogens is replaced by a trimethylamino group. A clinically used cardioprotective drug that is used for treatment of heart failure, myocardial infarction, arrhythmia, atherosclerosis and diabetes.

References

cas:76144-81-5
drugcentral:3995
kegg.drug:D10504
metacyc.compound:CPD-10661
pdb-ccd:REE
pubmed:23238051
pubmed:24124882
pubmed:24273007
pubmed:24571165
pubmed:24729295
pubmed:24754070
pubmed:24864465
pubmed:25001658
pubmed:25177785
pubmed:25177814
pubmed:25177815
pubmed:25446926
pubmed:25675721
pubmed:25702409
pubmed:25847280
pubmed:25902653
pubmed:26697890
pubmed:26761970
pubmed:26850121
pubmed:26961537
pubmed:27015859
reaxys:3938272
wikipedia.en:Meldonium

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from meldonium

Phenotype where environments contain meldonium

Phenotype modified by environments containing meldonium

Phenotype affecting meldonium

Human Disease Model