Search Ontology:
ChEBI
IWP-2
- Term ID
- CHEBI:125649
- Synonyms
-
- IWP 2
- IWP2
- N-(6-methyl-1,3-benzothiazol-2-yl)-2-[(4-oxo-3-phenyl-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]acetamide
- N-(6-methylbenzo[d]thiazol-2-yl)-2-(4-oxo-3-phenyl-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-ylthio)acetamide
- Definition
- A thienopyridine that is 6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one substituted by {2-[(6-methyl-1,3-benzothiazol-2-yl)amino]-2-oxoethyl}sulfanediyl and phenyl groups at positions 2 and 3, respectively. It is an ATP-competitive CK1delta inhibitor and also a Wnt/beta-catenin signal pathway inhibitor.
- References
-
- CAS:686770-61-6
- LINCS:LSM-37210
- PDBeChem:9XK
- PMID:23477365
- PMID:28685057
- PMID:29630366
- PMID:33249719
- PMID:35007292
- PMID:35533251
- PMID:35534526
- PMID:35855110
- PMID:36328429
- PMID:36414229
- PMID:37398564
- PMID:37774763
- PMID:37971040
- PMID:38560255
- PMID:39229572
- PMID:39313132
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from IWP-2
Phenotype where environments contain IWP-2
Phenotype modified by environments containing IWP-2
Human Disease Model