cefalotin

Term ID

CHEBI:124991

Synonyms

(6R,7R)-3-(acetoxymethyl)-8-oxo-7-(thiophen-2-ylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
3-Acetoxymethyl-7-(2-thienylacetamido)-3-cephem-4-carboxylic acid
7-(2'-thienylacetamido)cephalosporanic acid
7-(2-Thienylacetamido)cephalosporanic acid
7-(Thiophene-2-acetamido)cephalosporin
7beta-(thiophen-2-ylacetamido)-3-acetoxymethyl-3,4-didehydrocepham-4-carboxylic acid
Cefalothin
Cefalotin
cefalotina
cefalotine
cefalotinum
CEPHALOTHIN
Cephalotin
CET

Definition

A semisynthetic, first-generation cephalosporin antibiotic with acetoxymethyl and (2-thienylacetyl)nitrilo moieties at positions 3 and 7, respectively, of the core structure. Administered parenterally during surgery and to treat a wide spectrum of blood infections.

References

beilstein:945586
cas:153-61-7
drugbank:DB00456
drugcentral:574
hmdb:HMDB0014599
kegg.compound:C07761
kegg.drug:D07635
lincs.smallmolecule:LSM-15184
patent:FR1384197
patent:US3218318
pdb-ccd:CLS
pubmed:10930630
pubmed:12569987
pubmed:12833570
pubmed:1384868
pubmed:13963283
pubmed:1701026
pubmed:2083978
pubmed:23472927
pubmed:23680238
pubmed:29017833
pubmed:6176550
reaxys:945586
wikipedia.en:Cephalothin

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from cefalotin

Phenotype where environments contain cefalotin

Phenotype modified by environments containing cefalotin

Phenotype affecting cefalotin

Human Disease Model