Search Ontology:
ChEBI

compound E

Term ID
CHEBI:101713
Synonyms
  • gamma-secretase inhibitor XXI
  • N(2)-[(3,5-difluorophenyl)acetyl]-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-L-alaninamide
Definition
An L-alanine derivative that is the amide obtained by formal condensation of the carboxy group of N-[(3,5-difluorophenyl)acetyl]-L-alanine with the amino group of (3S)-3-amino-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one. An inhibitor of memapsin 2 (γ-secretase).
References
  • lincs.smallmolecule:LSM-42757
  • pubmed:32461793
  • pubmed:33732379
  • pubmed:33750924
  • reaxys:14671471
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from compound E
Phenotype where environments contain compound E
Phenotype modified by environments containing compound E
Phenotype affecting compound E
Human Disease Model