norfloxacin

Term ID

CHEBI:100246

Synonyms

1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsaeure
1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
NFLX
norfloxacin
norfloxacine
norfloxacino
norfloxacinum

Definition

A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.

References

cas:70458-96-7
drugbank:DB01059
drugcentral:1967
gmelin:1576626
hmdb:HMDB0015192
kegg.compound:C06687
kegg.drug:D00210
lincs.smallmolecule:LSM-5286
patent:BE863429
patent:DE2840910
patent:US4146719
patent:US4292317
pubmed:3317294
pubmed:3908074
pubmed:6211142
pubmed:6224685
pubmed:6234465
pubmed:6454381
pubmed:6461606
reaxys:567897
vsdb:1831
wikipedia.en:Norfloxacin

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from norfloxacin

Phenotype where environments contain norfloxacin

Phenotype modified by environments containing norfloxacin

Phenotype affecting norfloxacin

Human Disease Model