OBO ID: GO:0070268
Term Name: cornification Search Ontology:
Synonyms:
Definition: A type of programmed cell death that occurs in the epidermis, morphologically and biochemically distinct from apoptosis. It leads to the formation of corneocytes, i.e. dead keratinocytes containing an amalgam of specific proteins (e.g., keratin, loricrin, SPR and involucrin) and lipids (e.g., fatty acids and ceramides), which are necessary for the function of the cornified skin layer (mechanical resistance, elasticity, water repellence and structural stability). 18846107
References:
Ontology: GO: Biological Process    QuickGO    AmiGO
PHENOTYPE No data available