Term Name: |
granulocyte-macrophage colony-stimulating factor signaling pathway |
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Search Ontology:
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Synonyms: |
- CSF2 signaling pathway
- GM-CSF receptor signaling pathway
- GM-CSF signaling pathway
- granulocyte-macrophage colony-stimulating factor receptor signaling pathway
- granulocyte-macrophage colony-stimulating factor signalling pathway
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Definition: |
The series of molecular signals initiated by the binding of the cytokine granulocyte macrophage colony-stimulating factor (GM-CSF) to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. GM-CSF binds to a heterodimer receptor (CSF2R) consisting of an alpha ligand-binding subunit, and a common beta subunit that is shared with other cytokine receptors.
17027509
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References: |
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Ontology: |
GO: Biological Process
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