OBO ID: CHEBI:90531

Term Name:	sotrastaurin		Search Ontology:
Synonyms:	3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]-1H-pyrrole-2,5-dione AEB 071 AEB-071 AEB071 sotrastaurin sotrastaurina sotrastaurine sotrastaurinum
Definition:	A member of the class of maleimides that is maleimide which is substituted at position 3 by an indol-3-yl group and at position 4 by a quinazolin-4-yl group, which in turn is substituted at position 2 by a 4-methylpiperazin-1-yl group. It is a potent and selective inhibitor of protein kinase C and has been investigated as an immunosuppresant in renal transplant patients.
References:	CAS:425637-18-9 KEGG:D09671 LINCS:LSM-42761 PDBeChem:LW4 PMID:19491325 PMID:19827831 PMID:20003043 PMID:20683390 PMID:21142580 PMID:21157403 PMID:21324920 PMID:21564523 PMID:21883905 PMID:25634538 PMID:25677074 Reaxys:13012870
Ontology:	ChEBI  ( EBI )