OBO ID: CHEBI:90441

Term Name:	WIN 18446		Search Ontology:
Synonyms:	Fertilysin Fertilysine N,N'-1,8-Octanediylbis(2,2-dichloroacetamide) N,N'-bis(dichloracetyl)-1,8-octanediamine N,N'-bis(dichloroacetyl)-1,8-diaminooctane N,N'-bis(dichloroacetyl)-1,8-octamethylenediamine N,N'-octamethylenebis(2,2-dichloro-N-ethylacetamide) N,N'-octamethylenebis(2,2-dichloroacetamide) N,N'-octane-1,8-diylbis(2,2-dichloroacetamide) WIN 18,446 Win-18446 WIN18446
Definition:	A carboxamide that is 1,8-diaminooctane in which a hydrogen attached to each of the amino groups has been replaced by a dichloroacetyl group. Inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2). Inhibits the biosynthesis of retinoic acid from retinol in neonatal and adult murine testis. It down-regulates sex related genes in zebrafish.
References:	CAS:1477-57-2 PMID:14599310 PMID:3970137 PMID:6260633 PMID:8563190 Patent:US3143566 Reaxys:2136774
Ontology:	ChEBI  ( EBI )