OBO ID: CHEBI:76003
Term Name: afatinib dimaleate Search Ontology:
Synonyms:
  • (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide di[(2Z)-but-2-enedioate]
  • Afatinib maleate
  • BIBW 2992MA2
  • Gilotrif
Definition: A maleate salt obtained by combining afatinib with two molar equivalents of maleic acid. Used for the first-line treatment of patients with metastatic non-small cell lung cancer.
References:
  • CAS:850140-73-7
  • DrugBank:DB08916
  • KEGG:D09733
  • PMID:23982599
  • Patent:US2005085495
  • Patent:WO2012121764
  • Patent:WO2013052157
  • Reaxys:14383062
  • Wikipedia:Afatinib
Ontology: Chebi
PHENOTYPE No data available