ZFIN ChEBI: BGT226 free base

OBO ID: CHEBI:71967

Term Name:	BGT226 free base		Search Ontology:
Synonyms:	8-(6-methoxypyridin-3-yl)-3-methyl-1-[4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl]-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one
Definition:	An imidazoquinoline that is 3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinoline substituted at position 1 by a 3-trifluoromethyl-4-(piperazin-1-yl)phenyl group and at position 8 by a 6-methoxypyridin-3-yl group. A dual PI3K/mTOR inhibitor.
References:	LINCS:LSM-6710 Patent:WO2006122806 Reaxys:12748765
Ontology:	ChEBI ( EBI )

Relationships

is a type of:	aromatic ether imidazoquinoline N-arylpiperazine organofluorine compound pyridines aromatic ether imidazoquinoline N-arylpiperazine organofluorine compound pyridines Show first 5 Terms
has_role:	antineoplastic agent EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor mTOR inhibitor antineoplastic agent EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor mTOR inhibitor Show first 5 Terms
inverse is_conjugate_acid_of:	BGT226(1+) BGT226(1+) Show first 5 Terms
is_conjugate_base_of:	BGT226(1+) BGT226(1+) Show first 5 Terms

PHENOTYPE No data available