| OBO ID: CHEBI:64061 |
| Term Name: | CGP 78608 | Search Ontology: | |
|---|---|---|---|
| Synonyms: |
|
||
| Definition: | A phosphonic acid in which the hydrogen attached to phosphorous is substituted by a 1-{[(7-bromo-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)methyl]amino}ethyl group. Potent and selective NMDA antagonist that acts through the glycine site (IC50 = 5 nM). Displays >500-fold selectivity over kainate and AMPA receptors (IC50 values are 2.7 and 3 muM respectively). Anticonvulsant in vivo following systemic administration. | ||
| References: |
|
||
| Ontology: | ChEBI ( EBI ) |
Show first 5 Terms
PHENOTYPE
No data available
