OBO ID: CHEBI:50212
Term Name: pizotifen Search Ontology:
Synonyms:
  • 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine
  • pizotifen
  • pizotifene
  • pizotifeno
  • pizotifenum
  • Pizotyline
Definition: A benzocycloheptathiophene that is 9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophene 4-ylidene)-1-methylpiperidine which is joined from the 4 position to the 4 position of an N-methylpiperidine moiety by a double bond. It is a sedating antihistamine, with strong serotonin antagonist and weak antimuscarinic activity. It is generally used as the malate salt for the treatment of migraine and the prevention of headache attacks during cluster periods.
References:
  • Beilstein:753534
  • CAS:15574-96-6
  • Drug_Central:2220
  • KEGG:D05523
  • LINCS:LSM-3695
  • Patent:BE636717
  • Patent:US3272826
  • Reaxys:753534
  • Wikipedia:Pizotifen
Ontology: ChEBI  ( EBI )
PHENOTYPE No data available