OBO ID: CHEBI:31899

Term Name:	nemonapride		Search Ontology:
Synonyms:	(+-)-cis-N-(1-benzyl-2-methyl-3-pyrrolidinyl)-5-chloro-4-(methylamino)-o-anisamide (+-)-cis-N-(1-benzyl-2-methylpyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylaminobenzamide (+-)-nemonapride Emilace emonapride nemonaprida nemonapride nemonapridum rac-N-[(2S,3S)-1-benzyl-2-methylpyrrolidin-3-yl]-5-chloro-2-methoxy-4-(methylamino)benzamide rac-nemonapride racemic nemonapride YM 09151-2 YM-09151
Definition:	A racemate composed of (2S,3S)- and (2R,3R)-enantiomers of nemonapride. Highly potent dopamine D2-like receptor antagonist; selective over D1-like receptors (Ki values are 0.1 and 740 nM for D2-like and D1-like receptors respectively). Also potent 5-HT1A receptor agonist (IC50 = 34 nM) and has affinity for sigma receptors.
References:	CAS:75272-39-8 Drug_Central:1895 KEGG:C12915 KEGG:D01468 PMID:10049714 PMID:10363800 PMID:10435376 PMID:10587100 PMID:10823405 PMID:10862524 PMID:10898926 PMID:10917400 PMID:11817505 PMID:11929700 PMID:16020947 PMID:8328325 PMID:9016292 PMID:9031995 PMID:9095318 PMID:9228185 PMID:9310388 PMID:9325557 PMID:9369342 PMID:9766869 PMID:9774248 PMID:9934942 Patent:EP1273301 Patent:US5811547 Reaxys:5766104 Wikipedia:Nemonapride
Ontology:	ChEBI  ( EBI )