Term Name: |
angiotensin I |
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Search Ontology:
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Synonyms: |
- angiotensin I
- Angiotonin
- Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu
- D-R-V-Y-I-H-P-F-H-L
- DRVYIHPFHL
- Hypertensin
- L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanyl-L-histidyl-L-leucine
- L-Asp-L-Arg-L-Val-L-Tyr-L-Ile-L-His-L-Pro-L-Phe-L-His-L-Leu
- pepsitensin
- proangiotensin
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Definition: |
A ten amino acid peptide formed by renin cleavage of angiotensinogen. Angiotensin I has no direct biological function except that high levels can stimulate catecholamine production. It is metabolized to its biologically active byproduct angiotensin II, a potent vasoconstrictor, by angiotensin converting enzyme (ACE) through cleavage of the two terminal amino acids.
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References: |
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Ontology: |
ChEBI
(
EBI
)
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