OBO ID: CHEBI:193597 |
Term Name: | ARS-1620 | Search Ontology: | |
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Definition: | A qinazoline derivative carrying chloro and fluoro substituents at positions 6 and 8 respectively, a 2-fluoro-6-hydroxyphenyl group at position 7, and a 4-(prop-2-enoyl)piperazin-1-yl group at position 4. A potent, selective, and orally bioavailable covalent KRAS-G12C inhibitor, it inhibits the protein coding gene KRAS (Kirsten rat sarcoma virus) with high potency in cells and animals. | ||
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Ontology: | ChEBI ( EBI ) |
PHENOTYPE
No data available