OBO ID: CHEBI:191940

Term Name:	ponatinib hydrochloride		Search Ontology:
Synonyms:	3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide hydrochloride 3-[(imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide--hydrogen chloride 4-{4-[3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzamido]-2-(trifluoromethyl)benzyl}-1-methylpiperazin-1-ium chloride 4-{[4-{3-[(imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methylbenzamido}-2-(trifluoromethyl)phenyl]methyl}-1-methylpiperazin-1-ium chloride AP 24534 hydrochloride AP-24534 hydrochloride AP24534 HCl Iclusig ponatinib HCl
Definition:	The hydrochloride salt of ponatinib. It is a potent pan inhibitor of tyrosine kinases, active in all single resistance ABL kinase mutations including the T315l mutation. It is approved for the treatment of chronic myeloid leukemia.
References:	CAS:1114544-31-8 Chemspider:28527869 DrugBank:DBSALT000142 KEGG:D09951 PMID:19878872 PMID:25970013 PMID:28690276 PMID:28978814 PMID:29966620 PMID:30705592 PMID:34810285
Ontology:	ChEBI  ( EBI )