OBO ID: CHEBI:127780
Term Name: phosphonoformic acid Search Ontology:
Synonyms:
  • carboxyphosphonic acid
  • dihydroxyphosphanecarboxylic acid oxide
  • Foscarmet
  • FOSCARNET
  • PHOSPHONOFORMIC ACID
  • phosphonomethanoic acid
Definition: Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.
References:
Ontology: Chebi
PHENOTYPE No data available