| Term: | macrophage granuloma formation |
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| Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
| Name: | macrophage |
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| Synonyms: | histiocyte |
| Definition: | A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. |
| Ontology: | Anatomy Ontology [ZFA:0009141] |
| Name: | granuloma formation |
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| Synonyms: | |
| Definition: | The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic. |
| Ontology: | GO: Biological Process [GO:0002432] QuickGO AmiGO |