| Term: | brain neurofibrillary tangle |
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| Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
| Name: | brain |
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| Synonyms: | brain structure |
| Definition: | Cavitated compound organ which is comprised of gray and white matter and surrounds the cerebral ventricular system. |
| Ontology: | Anatomy Ontology [ZFA:0000008] |
| Name: | neurofibrillary tangle |
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| Synonyms: | flame-shaped neurofibrillary tangle, star-shaped neurofibrillary tangle |
| Definition: | Intracellular mass of paired, helically wound protein filaments (also called PHF) lying in the cytoplasm of neuronal cell bodies and neuritic cell processes. Neurofibrillary tangles contain an abnormally phosphorylated form of a microtubule-associated protein, tau. The shape of these inclusions may resemble a flame or a star. |
| Ontology: | GO: Cellular Component [GO:0097418] QuickGO AmiGO |