Term: | keratinocyte site of DNA damage |
---|---|
Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
Name: | keratinocyte |
---|---|
Synonyms: | keratinocytes |
Definition: | An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell. |
Ontology: | Anatomy Ontology [ZFA:0009158] |
Name: | site of DNA damage |
---|---|
Synonyms: | |
Definition: | A region of a chromosome at which DNA damage has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix. |
Ontology: | GO: Cellular Component [GO:0090734] QuickGO AmiGO |