Term: | Rohon-Beard neuron clustering of voltage-gated sodium channels |
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Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
Name: | Rohon-Beard neuron |
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Synonyms: | RB neuron, Rohon-Beard cell, Rohon-Beard neurons |
Definition: | Primary sensory neurons with cell bodies located in the dorsal spinal cord, that innervate the integument of the trunk and tail at early larval stages. The cutaneous axons of Rohon-Beard neurons display a broad spectrum of peripheral axon branching patterns. Most Rohon-Beard neurons undergo apoptosis by 5dpf. |
Ontology: | Anatomy Ontology [ZFA:0009150] |
Name: | clustering of voltage-gated sodium channels |
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Synonyms: | clustering of voltage gated sodium channels, clustering of voltage-dependent sodium channels, Nav channel clustering, voltage-gated sodium channel clustering |
Definition: | The process in which voltage-gated sodium channels become localized together in high densities. In animals, nodes of Ranvier differ dramatically from internodal axonal regions in very high densities of voltage-dependent sodium (Nav) channels responsible for the rapid, inward ionic currents that produce membrane depolarization. |
Ontology: | GO: Biological Process [GO:0045162] QuickGO AmiGO |