| Term: | intervertebral ligament cell death |
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| Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
| Name: | intervertebral ligament |
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| Synonyms: | annulus fibrosus, IVL |
| Definition: | Ligament that connects adjacent vertebra. The intervertebral ligament (IVL) connects the posterior vertebral end plate to the anterior vertebral end plate of adjacent vertebra. For example the IVL connects the posterior end plate of vertebra 14 to the anterior end plate of vertebra 15. It is typically composed of three distinct layers: the notochord sheath which is mainly type II collagen; the outer elastin layer; and a layer of type I collagen fiber bundles. |
| Ontology: | Anatomy Ontology [ZFA:0007119] |
| Name: | cell death |
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| Synonyms: | accidental cell death, necrosis |
| Definition: | Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538). |
| Ontology: | GO: Biological Process [GO:0008219] QuickGO AmiGO |