| Term: | ciliary marginal zone cell death |
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| Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
| Name: | ciliary marginal zone |
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| Synonyms: | circumferential germinal zone, CMZ, peripheral growth zone, retinal ciliary marginal zone, retinal proliferative zone |
| Definition: | Proliferative region at the periphery of the retina where retinal stem cells are located. After 60 hpf, the CMZ is the source of most retinal growth. |
| Ontology: | Anatomy Ontology [ZFA:0001289] |
| Name: | cell death |
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| Synonyms: | accidental cell death, necrosis |
| Definition: | Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538). |
| Ontology: | GO: Biological Process [GO:0008219] QuickGO AmiGO |