| Term: | Kupffer's vesicle cell death |
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| Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
| Name: | Kupffer's vesicle |
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| Synonyms: | ciliated organ of asymmetry |
| Definition: | Small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period. Kupffer's vesicle has been compared to the mouse embryonic node. |
| Ontology: | Anatomy Ontology [ZFA:0000001] |
| Name: | cell death |
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| Synonyms: | accidental cell death, necrosis |
| Definition: | Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538). |
| Ontology: | GO: Biological Process [GO:0008219] QuickGO AmiGO |