| Term: | brain G protein-coupled receptor signaling pathway |
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| Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
| Name: | brain |
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| Synonyms: | brain structure |
| Definition: | Cavitated compound organ which is comprised of gray and white matter and surrounds the cerebral ventricular system. |
| Ontology: | Anatomy Ontology [ZFA:0000008] |
| Name: | G protein-coupled receptor signaling pathway |
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| Synonyms: | dimeric G-protein coupled receptor signaling pathway, dimeric G-protein coupled receptor signalling pathway, G protein coupled receptor protein signaling pathway, G protein coupled receptor protein signalling pathway, G-protein coupled receptor protein signal transduction, G-protein coupled receptor protein signaling pathway, G-protein coupled receptor signaling pathway via GPCR dimer, G-protein coupled receptor signalling pathway, G-protein-coupled receptor protein signalling pathway, GPCR signaling pathway, GPCR signalling pathway |
| Definition: | The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. |
| Ontology: | GO: Biological Process [GO:0007186] QuickGO AmiGO |