ZFIN Post-Composed Term: pancreas apoptotic process

Term:	pancreas apoptotic process
Note:	This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name.

Name:	pancreas
Synonyms:
Definition:	The pancreas is an organ composed of endocrine and exocrine glandular tissue that produce hormones and digestive enzymes. Unlike in other studied vertebrates the pancreas in zebrafish develops from two buds, one anterior and one posterior. In adult fish the main pancreas is located on the right side attached to the lateral aspect of the intestine by the pancreatic duct. Typically, one large islet and 3-6 smaller islets occupy the main pancreas. The tail of the pancreas is embedded with single beta cells or clusters of small islets and extends caudally along the right side of the intestine.
Ontology:	Anatomy Ontology [ZFA:0000140]

Name:	apoptotic process
Synonyms:	apoptosis, apoptosis activator activity, apoptosis signaling, apoptotic cell death, apoptotic program, apoptotic programmed cell death, caspase-dependent programmed cell death, cell suicide, cellular suicide, commitment to apoptosis, induction of apoptosis, induction of apoptosis by p53, programmed cell death by apoptosis, signaling (initiator) caspase activity, type I programmed cell death
Definition:	A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
Ontology:	GO: Biological Process [GO:0006915] QuickGO AmiGO