Gene
znf408
- ID
- ZDB-GENE-130530-589
- Name
- zinc finger protein 408
- Symbol
- znf408 Nomenclature History
- Previous Names
-
- zmp:0000000586
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have metal ion binding activity and nucleic acid binding activity. Involved in retina vasculature development in camera-type eye. Predicted to localize to nucleus. Used to study exudative vitreoretinopathy. Human ortholog(s) of this gene implicated in exudative vitreoretinopathy 6 and retinitis pigmentosa 72. Orthologous to human ZNF408 (zinc finger protein 408).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| exudative vitreoretinopathy 6 | Alliance | ?Exudative vitreoretinopathy 6 | 616468 |
| retinitis pigmentosa 72 | Alliance | Retinitis pigmentosa 72 | 616469 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| exudative vitreoretinopathy | y1Tg + MO1-znf408 | standard conditions | Collin et al., 2013 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | PRDM17, PR/SET domain | SET domain | SET domain superfamily | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|---|---|
|
UniProtKB:E7FAN3
|
764 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
znf408-201
(1)
|
Ensembl | 2,474 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance