Gene
cdc14ab
- ID
- ZDB-GENE-070705-309
- Name
- cell division cycle 14Ab
- Symbol
- cdc14ab Nomenclature History
- Previous Names
-
- cdc14a2 (1)
- si:dkey-168j9.1
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to have protein serine/threonine phosphatase activity and protein tyrosine phosphatase activity. Predicted to be involved in several processes, including cilium assembly; positive regulation of cytokinesis; and regulation of mitotic cell cycle. Predicted to localize to cytoplasm; microtubule cytoskeleton; and nucleolus. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 32. Orthologous to human CDC14A (cell division cycle 14A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive nonsyndromic deafness 32 | Alliance | Deafness, autosomal recessive 32, with or without immotile sperm | 608653 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR016130 | Protein-tyrosine phosphatase, active site |
| Domain | IPR000340 | Dual specificity phosphatase, catalytic domain |
| Domain | IPR000387 | Tyrosine-specific protein phosphatases domain |
| Domain | IPR020422 | Dual specificity protein phosphatase domain |
| Domain | IPR029260 | Dual specificity/tyrosine protein phosphatase, N-terminal |
| Domain | IPR044506 | Dual-specificity phosphatase CDC14, C-terminal |
| Family | IPR050561 | Protein Tyrosine Phosphatase |
| Homologous_superfamily | IPR029021 | Protein-tyrosine phosphatase-like |
Domain Details Per Protein
| Protein | Length | Dual specificity phosphatase, catalytic domain | Dual-specificity phosphatase CDC14, C-terminal | Dual specificity protein phosphatase domain | Dual specificity/tyrosine protein phosphatase, N-terminal | Protein Tyrosine Phosphatase | Protein-tyrosine phosphatase, active site | Protein-tyrosine phosphatase-like | Tyrosine-specific protein phosphatases domain |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PDX1
|
595 | ||||||||
|
UniProtKB:A5PMX2
|
510 | ||||||||
|
UniProtKB:A0A0R4IVA4
|
611 | ||||||||
|
UniProtKB:A0A8M9PJL3
|
537 | ||||||||
|
UniProtKB:A0A8M2B8K4
|
509 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cdc14ab-201
(1)
|
Ensembl | 4,436 nt | ||
| mRNA |
cdc14ab-202
(1)
|
Ensembl | 510 nt | ||
| mRNA |
cdc14ab-203
(1)
|
Ensembl | 5,359 nt |
Interactions and Pathways
No data available
Plasmids
No data available