Gene

pm20d1.2

ID
ZDB-GENE-061013-637
Name
peptidase M20 domain containing 1, tandem duplicate 2
Symbol
pm20d1.2 Nomenclature History
Previous Names
  • zgc:154035
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides. Predicted to be involved in several processes, including adaptive thermogenesis; energy homeostasis; and regulation of oxidative phosphorylation uncoupler activity. Predicted to localize to extracellular space. Orthologous to human PM20D1 (peptidase M20 domain containing 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pm20d1.2 Human Ortholog
No data available
Associated With pm20d1.2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR011650 Peptidase M20, dimerisation domain
Family IPR002933 Peptidase M20
Family IPR017141 Peptidase M20, carboxypeptidase S
Family IPR047177 Peptidase M20A
Homologous_superfamily IPR036264 Bacterial exopeptidase dimerisation domain
Domain Details Per Protein
Protein Length Bacterial exopeptidase dimerisation domain Peptidase M20 Peptidase M20A Peptidase M20, carboxypeptidase S Peptidase M20, dimerisation domain
UniProtKB:B2GT51 522
UniProtKB:A0A8M9PKV1 522
UniProtKB:Q08BB2 522
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA pm20d1.2-201 (1) Ensembl 3,959 nt
ncRNA pm20d1.2-002 (1) Ensembl 489 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Note
Zebrafish genes pm20d1.1 and pm20d1.2 are likely tandem duplicates as they are next to each other in the genome, are similar, and not part of a gene family. Also, the amino acid sequence of both genes shows identity to single human PM20D1 and mouse Pm20d1 genes and is further supported by conserved location.
Citations