ZFIN is now using GRCz12tu for Genomic Data
Gene
tyw2
- ID
- ZDB-GENE-060825-182
- Name
- tRNA wybutosine-synthesizing protein 2
- Symbol
- tyw2 Nomenclature History
- Previous Names
-
- trmt12 (1)
- zgc:153361
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable tRNA methyltransferase activity. Predicted to be involved in tRNA methylation and wybutosine biosynthetic process. Predicted to be active in cytoplasm. Orthologous to human TYW2 (tRNA wybutosine-synthesizing protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Bazzini et al., 2016
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR030382 | SAM-dependent methyltransferase TRM5/TYW2-type |
| Domain | IPR056743 | TRM5/TYW2-like, methyltransferase domain |
| Domain | IPR056744 | TRM5/TYW2-like, N-terminal domain |
| Domain | IPR056745 | TYW2, N-terminal domain |
| Homologous_superfamily | IPR029063 | S-adenosyl-L-methionine-dependent methyltransferase superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | S-adenosyl-L-methionine-dependent methyltransferase superfamily | SAM-dependent methyltransferase TRM5/TYW2-type | TRM5/TYW2-like, methyltransferase domain | TRM5/TYW2-like, N-terminal domain | TYW2, N-terminal domain |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q0P466 | InterPro | 408 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
trmt12-201
(1)
|
Ensembl | 1,439 nt | ||
| mRNA |
trmt12-202
(1)
|
Ensembl | 924 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers