Gene
gpt
- ID
- ZDB-GENE-050302-11
- Name
- glutamic--pyruvic transaminase
- Symbol
- gpt Nomenclature History
- Previous Names
-
- gpt2
- gpt2l
- im:6791811
- wu:fd46f01
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have L-alanine:2-oxoglutarate aminotransferase activity. Predicted to be involved in 2-oxoglutarate metabolic process and L-alanine metabolic process. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Is expressed in liver. Orthologous to several human genes including GPT (glutamic--pyruvic transaminase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR004839 | Aminotransferase, class I/classII, large domain |
| Family | IPR045088 | Aminotransferase ALAT1/2-like |
| Homologous_superfamily | IPR015421 | Pyridoxal phosphate-dependent transferase, major domain |
| Homologous_superfamily | IPR015422 | Pyridoxal phosphate-dependent transferase, small domain |
| Homologous_superfamily | IPR015424 | Pyridoxal phosphate-dependent transferase |
Domain Details Per Protein
| Protein | Length | Aminotransferase ALAT1/2-like | Aminotransferase, class I/classII, large domain | Pyridoxal phosphate-dependent transferase | Pyridoxal phosphate-dependent transferase, major domain | Pyridoxal phosphate-dependent transferase, small domain |
|---|---|---|---|---|---|---|
|
UniProtKB:Q6NYL5
|
549 | |||||
|
UniProtKB:A0A8M1NQS1
|
493 |
Interactions and Pathways
No data available
Plasmids
No data available