Gene

impact

ID

ZDB-GENE-040927-10

Name

impact RWD domain protein

Symbol

impact Nomenclature History

Previous Names

zgc:103672 (1)

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Predicted to enable protein sequestering activity. Predicted to be involved in several processes, including GCN2-mediated signaling; cellular response to amino acid starvation; and regulation of gene expression. Predicted to act upstream of or within cell differentiation; nervous system development; and regulation of translation. Predicted to be active in cytoplasm. Orthologous to human IMPACT (impact RWD domain protein).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:103672 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With impact Human Ortholog

No data available

Associated With impact Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR020569	Uncharacterised protein family UPF0029, Impact, conserved site
Domain	IPR001498	Impact, N-terminal
Domain	IPR006575	RWD domain
Family	IPR023582	Impact family
Homologous_superfamily	IPR016135	Ubiquitin-conjugating enzyme/RWD-like
Homologous_superfamily	IPR020568	Ribosomal protein uS5 domain 2-type superfamily
Homologous_superfamily	IPR036956	Impact, N-terminal domain superfamily

Domain Details Per Protein

Protein	Length	Impact family	Impact, N-terminal	Impact, N-terminal domain superfamily	Ribosomal protein uS5 domain 2-type superfamily	RWD domain	Ubiquitin-conjugating enzyme/RWD-like	Uncharacterised protein family UPF0029, Impact, conserved site
UniProtKB:Q642J4 InterPro	317
UniProtKB:A0A8M9PDU7 InterPro	201
UniProtKB:A0A8M6YX97 InterPro	245
UniProtKB:F1R3T9 InterPro	317

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	impact-201 (1) Ensembl	Ensembl	1,436 nt	Select Tool ZFIN BLAST
mRNA	impact-202 (1) Ensembl	Ensembl	448 nt	Select Tool ZFIN BLAST
mRNA	impact-203 (1) Ensembl	Ensembl	453 nt	Select Tool ZFIN BLAST
mRNA	impact-204 (1) Ensembl	Ensembl	514 nt	Select Tool ZFIN BLAST
mRNA	impact-205 (1) Ensembl	Ensembl	1,569 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations