Gene

atg4b

ID
ZDB-GENE-040917-3
Name
autophagy related 4B, cysteine peptidase
Symbol
atg4b Nomenclature History
Previous Names
  • apg4b (1)
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have cysteine-type endopeptidase activity. Predicted to be involved in autophagy; protein transport; and proteolysis. Predicted to localize to cytoplasm. Is expressed in brain; liver; and muscle. Orthologous to human ATG4B (autophagy related 4B cysteine peptidase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Meng et al., 2017
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With atg4b Human Ortholog
No data available
Associated With atg4b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR046793 Cysteine protease ATG4, F-type LIR motif
Domain IPR046792 Peptidase C54, catalytic domain
Family IPR005078 Peptidase C54
Homologous_superfamily IPR038765 Papain-like cysteine peptidase superfamily
Domain Details Per Protein
Protein Length Cysteine protease ATG4, F-type LIR motif Papain-like cysteine peptidase superfamily Peptidase C54 Peptidase C54, catalytic domain
UniProtKB:A4QN52 394
UniProtKB:A0A8M2BD94 424
UniProtKB:Q6DG88 394
UniProtKB:A0A8M6YZJ8 354
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
aberrant processed transcript atg4b-202 (1) Ensembl 1,343 nt
mRNA atg4b-201 (1) Ensembl 1,824 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations