Gene
fgf17
- ID
- ZDB-GENE-040621-1
- Name
- fibroblast growth factor 17
- Symbol
- fgf17 Nomenclature History
- Previous Names
-
- fgf17b
- zgc:101759
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable growth factor activity; type 1 fibroblast growth factor receptor binding activity; and type 2 fibroblast growth factor receptor binding activity. Involved in anterior/posterior pattern specification; mesoderm development; and nervous system development. Acts upstream of or within negative regulation of endodermal cell fate specification. Predicted to be located in extracellular region. Predicted to be active in cytoplasm and extracellular space. Is expressed in several structures, including blastomere; cardiovascular system; forebrain; paraxial mesoderm; and sensory system. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 20 with or without anosmia. Orthologous to human FGF17 (fibroblast growth factor 17).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 23 figures from 11 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7139635 (100 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hypogonadotropic hypogonadism 20 with or without anosmia | Alliance | Hypogonadotropic hypogonadism 20 with or without anosmia | 615270 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytokine IL1/FGF | Fibroblast growth factor family |
|---|---|---|---|
|
UniProtKB:A0A8M2BJU5
|
203 | ||
|
UniProtKB:B2GR83
|
215 | ||
|
UniProtKB:Q6SJP8
|
215 |
Interactions and Pathways
Plasmids
No data available