Gene
spred2b
- ID
- ZDB-GENE-040426-2342
- Name
- sprouty related EVH1 domain containing 2b
- Symbol
- spred2b Nomenclature History
- Previous Names
-
- spred2
- fb93f08
- wu:fb93f08
- zgc:77284
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have protein kinase binding activity. Predicted to be involved in positive regulation of DNA damage response, signal transduction by p53 class mediator and regulation of protein modification process. Predicted to localize to plasma membrane and transport vesicle membrane. Is expressed in brain and spinal cord. Orthologous to human SPRED2 (sprouty related EVH1 domain containing 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Noonan syndrome 14 | 619745 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | c-Kit-binding domain | PH-like domain superfamily | SPRE, EVH1 domain | Sprouty | WH1/EVH1 domain |
|---|---|---|---|---|---|---|
|
UniProtKB:Q6NYK3
|
413 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
spred2b-201
(1)
|
Ensembl | 3,030 nt |
Interactions and Pathways
No data available
Plasmids
No data available