Gene

ifi30a

ID

ZDB-GENE-030131-8447

Name

IFI30 lysosomal thiol reductase a

Symbol

ifi30a Nomenclature History

Previous Names

GILT (1)
ifi30 (1)
LycGILT (1)
wu:fb12b04
zgc:101752

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Exhibits protein-disulfide reductase activity. Predicted to be involved in immune system process and oxidation-reduction process. Predicted to localize to extracellular region and lysosome. Is expressed in gut; pronephros; vein; and yolk syncytial layer. Orthologous to human IFI30 (IFI30 lysosomal thiol reductase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

11 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:7149228 (10 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Cacialli et al., 2021
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ifi30a Human Ortholog

No data available

Associated With ifi30a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003119	Saposin A-type domain
Family	IPR004911	Gamma interferon inducible lysosomal thiol reductase GILT

Domain Details Per Protein

Protein	Length	Gamma interferon inducible lysosomal thiol reductase GILT	Saposin A-type domain
UniProtKB:Q5XJN2 InterPro	255

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	ifi30-201 (1) Ensembl	Ensembl		1,041 nt	Select Tool
ncRNA	ifi30-002 (1) Ensembl	Ensembl		1,041 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations