ZFIN is now using GRCz12tu for Genomic Data
Gene
baz1b
- ID
- ZDB-GENE-010328-16
- Name
- bromodomain adjacent to zinc finger domain, 1B
- Symbol
- baz1b Nomenclature History
- Previous Names
-
- fi60d02
- im:7137554
- wu:fi60d02 (1)
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable histone H2AXY142 kinase activity and histone binding activity. Predicted to be involved in DNA damage response; chromatin remodeling; and post-translational protein modification. Predicted to be located in nucleus. Predicted to be part of WICH complex. Is expressed in dorsal telencephalon. Used to study Williams-Beuren syndrome. Orthologous to human BAZ1B (bromodomain adjacent to zinc finger domain 1B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7137554 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Torres-Pérez et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| Williams-Beuren syndrome | baz1bqm1/qm1 (TU) | control | Torres-Pérez et al., 2025 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019786 | Zinc finger, PHD-type, conserved site |
| Domain | IPR001487 | Bromodomain |
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR001965 | Zinc finger, PHD-type |
| Domain | IPR013136 | WSTF/Acf1/Cbp146 |
| Domain | IPR018501 | DDT domain |
| Domain | IPR019787 | Zinc finger, PHD-finger |
| Domain | IPR028941 | WHIM2 domain |
| Domain | IPR028942 | WHIM1 domain |
| Domain | IPR037375 | Tyrosine-protein kinase BAZ1B, bromodomain |
| Domain | IPR047256 | Tyrosine-protein kinase BAZ1B, PHD finger |
| Family | IPR047174 | Tyrosine-protein kinase BAZ1B |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR036427 | Bromodomain-like superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Bromodomain | Bromodomain-like superfamily | DDT domain | Tyrosine-protein kinase BAZ1B | Tyrosine-protein kinase BAZ1B, bromodomain | Tyrosine-protein kinase BAZ1B, PHD finger | WHIM1 domain | WHIM2 domain | WSTF/Acf1/Cbp146 | Zinc finger, FYVE/PHD-type | Zinc finger, PHD-finger | Zinc finger, PHD-type | Zinc finger, PHD-type, conserved site | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A2BIL7 | InterPro | 1536 | |||||||||||||||
| UniProtKB:A0A8M1P9M0 | InterPro | 1807 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers