Gene
tcf7
- ID
- ZDB-GENE-050222-4
- Name
- transcription factor 7
- Symbol
- tcf7 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and beta-catenin binding activity. Involved in pectoral fin development; regulation of transcription by RNA polymerase II; and spinal cord dorsal/ventral patterning. Predicted to localize to nucleus and transcription factor complex. Is expressed in several structures, including dermal bone; nervous system; optic cup; pectoral fin bud; and prechordal plate. Orthologous to human TCF7 (transcription factor 7).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 23 figures from 17 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR009071 | High mobility group box domain |
Domain | IPR013558 | CTNNB1 binding, N-teminal |
Family | IPR024940 | Transcription factor TCF/LEF |
Homologous_superfamily | IPR027397 | Catenin binding domain superfamily |
Homologous_superfamily | IPR036910 | High mobility group box domain superfamily |
Domain Details Per Protein
Protein | Length | Catenin binding domain superfamily | CTNNB1 binding, N-teminal | High mobility group box domain | High mobility group box domain superfamily | Transcription factor TCF/LEF |
---|---|---|---|---|---|---|
UniProtKB:Q5PU93
|
355 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
tcf7-201
(1)
|
Havana | 803 nt | |
mRNA |
tcf7-202
(1)
|
Havana | 924 nt | |
mRNA |
tcf7-203
(1)
|
Havana | 939 nt | |
mRNA |
tcf7-204
(1)
|
Havana | 767 nt | |
mRNA |
tcf7-205
(1)
|
Havana | 792 nt | |
mRNA |
tcf7-206
(1)
|
Ensembl | 1634 nt | |
mRNA |
tcf7-207
(1)
|
Ensembl | 1327 nt | |
mRNA |
tcf7-208
(1)
|
Ensembl | 1643 nt | |
mRNA |
tcf7-209
(1)
|
Ensembl | 1580 nt |
Interactions and Pathways
No data available
Plasmids
No data available