ZFIN

ZFIN ID: ZDB-TGCONSTRCT-170616-4

CITATIONS (3 total)

Transgenic Construct Name:	Tg(UAS:Dendra2-Hsa.MAPT_A152T,myl7:EGFP)
Transgenic Construct Symbol:	Tg(UAS:Dendra2-Hsa.MAPT_A152T,myl7:EGFP)

VerPlank, J.J.S., Tyrkalska, S.D., Fleming, A., Rubinsztein, D.C., Goldberg, A.L. (2020) cGMP via PKG activates 26S proteasomes and enhances degradation of proteins, including ones that cause neurodegenerative diseases. Proceedings of the National Academy of Sciences of the United States of America. 117(25):14220-14230

Siddiqi, F.H., Menzies, F.M., Lopez, A., Stamatakou, E., Karabiyik, C., Ureshino, R., Ricketts, T., Jimenez-Sanchez, M., Esteban, M.A., Lai, L., Tortorella, M.D., Luo, Z., Liu, H., Metzakopian, E., Fernandes, H.J.R., Bassett, A., Karran, E., Miller, B.L., Fleming, A., Rubinsztein, D.C. (2019) Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing. Nature communications. 10:1817

Lopez, A., Lee, S.E., Wojta, K., Ramos, E.M., Klein, E., Chen, J., Boxer, A.L., Gorno-Tempini, M.L., Geschwind, D.H., Schlotawa, L., Ogryzko, N.V., Bigio, E.H., Rogalski, E., Weintraub, S., Mesulam, M.M., Fleming, A., Coppola, G., Miller, B.L., Rubinsztein, D.C. (2017) A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction. Brain : a journal of neurology. 140(4):1128-1146