ZFIN

ZFIN ID: ZDB-GENE-090507-2

CITATIONS (39 total)

Gene Name:	toll-like receptor 4a, like
Gene Symbol:	tlr4al

Ni, Y., Zhang, Y., Zheng, L., Rong, N., Yang, Y., Gong, P., Yang, Y., Siwu, X., Zhang, C., Zhu, L., Fu, Z. (2023) Bifidobacterium and Lactobacillus improve inflammatory bowel disease in zebrafish of different ages by regulating the intestinal mucosal barrier and microbiota. Life sciences. 324:121699

Deng, Z., Hou, K., Valencak, T.G., Luo, X.M., Liu, J., Wang, H. (2022) AI-2/LuxS Quorum Sensing System Promotes Biofilm Formation of Lactobacillus rhamnosus GG and Enhances the Resistance to Enterotoxigenic Escherichia coli in Germ-Free Zebrafish. Microbiology spectrum. 10(4):e0061022

Chen, J., Tchivelekete, G.M., Zhou, X., Tang, W., Liu, F., Liu, M., Zhao, C., Shu, X., Zeng, Z. (2021) Anti-inflammatory activities of Gardenia jasminoides extracts in retinal pigment epithelial cells and zebrafish embryos. Experimental and Therapeutic Medicine. 22:700

Loes, A.N., Hinman, M.N., Farnsworth, D.R., Miller, A.C., Guillemin, K., Harms, M.J. (2021) Identification and Characterization of Zebrafish Tlr4 Coreceptor Md-2. Journal of immunology (Baltimore, Md. : 1950). 206(5):1046-1057

Luo, T., Wang, X., Jin, Y. (2021) Low concentrations of imidacloprid exposure induced gut toxicity in adult zebrafish (Danio rerio). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 241:108972

Sireswar, S., Dey, G., Biswas, S. (2021) Influence of fruit-based beverages on efficacy of Lacticaseibacillus rhamnosus GG (Lactobacillus rhamnosus GG) against DSS-induced intestinal inflammation. Food research international (Ottawa, Ont.). 149:110661

Tang, H.P., Huang, C., Hu, C.B., Li, H., Shao, T., Ji, J.F., Bai, J., Fan, D.D., Lin, A.F., Xiang, L.X., Shao, J.Z. (2021) Inhibitory Role of an Aeromonas hydrophila TIR Domain Effector in Antibacterial Immunity by Targeting TLR Signaling Complexes in Zebrafish. Frontiers in microbiology. 12:694081

Cheng, B., Zhang, H., Hu, J., Peng, Y., Yang, J., Liao, X., Liu, F., Guo, J., Hu, C., Lu, H. (2020) The immunotoxicity and neurobehavioral toxicity of zebrafish induced by famoxadone-cymoxanil. Chemosphere. 247:125870

Cornet, V., Douxfils, J., Mandiki, S.N.M., Kestemont, P. (2020) Early-life infection with a bacterial pathogen increases expression levels of innate immunity related genes during adulthood in zebrafish. Developmental and comparative immunology. 108:103672

Liyanage, T.D., Dahanayake, P.S., Edirisinghe, S.L., Nikapitiya, C., Heo, G.J., De Zoysa, M., Whang, I. (2020) Biological Activity of Porcine Gastric Mucin on Stress Resistance and Immunomodulation. Molecules. 25(13):

Pacheco, I., Contreras, M., Villar, M., Risalde, M.A., Alberdi, P., Cabezas-Cruz, A., Gortázar, C., de la Fuente, J. (2020) Vaccination with Alpha-Gal Protects Against Mycobacterial Infection in the Zebrafish Model of Tuberculosis. Vaccines. 8(2):

Aksakal, F.I., Ciltas, A. (2019) Impact of copper oxide nanoparticles (CuO NPs) exposure on embryo development and expression of genes related to the innate immune system of zebrafish (Danio rerio). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 223:78-87

Cheng, B., Zhang, H., Jia, K., Li, E., Zhang, S., Yu, H., Cao, Z., Xiong, G., Hu, C., Lu, H. (2019) Effects of spinetoram on the developmental toxicity and immunotoxicity of zebrafish. Fish & shellfish immunology. 96:114-121

Edirisinghe, S.L., Dananjaya, S.H.S., Nikapitiya, C., Liyanage, T.D., Lee, K.A., Oh, C., Kang, D.H., De Zoysa, M. (2019) Novel pectin isolated from Spirulina maxima enhances the disease resistance and immune responses in zebrafish against Edwardsiella piscicida and Aeromonas hydrophila. Fish & shellfish immunology. 94:558-565

Icoglu Aksakal, F., Ciltas, A., Simsek Ozek, N. (2019) A holistic study on potential toxic effects of carboxylated multi-walled carbon nanotubes (MWCNTs-COOH) on zebrafish (Danio rerio) embryos/larvae. Chemosphere. 225:820-828

Arias-Jayo, N., Abecia, L., Alonso-Sáez, L., Ramirez-Garcia, A., Rodriguez, A., Pardo, M.A. (2018) High-Fat Diet Consumption Induces Microbiota Dysbiosis and Intestinal Inflammation in Zebrafish. Microbial ecology. 76(4):1089-1101

Deng, S., Jia, P.P., Zhang, J.H., Junaid, M., Niu, A., Ma, Y.B., Fu, A., Pei, D.S. (2018) Transcriptomic response and perturbation of toxicity pathways in zebrafish larvae after exposure to graphene quantum dots (GQDs). Journal of hazardous materials. 357:146-158

Pérez-Ramos, A., Mohedano, M.L., Pardo, M.Á., López, P. (2018) β-Glucan-Producing Pediococcus parvulus 2.6: Test of Probiotic and Immunomodulatory Properties in Zebrafish Models.. Frontiers in microbiology. 9:1684

Xiong, G., Zou, L., Deng, Y., Meng, Y., Liao, X., Lu, H. (2018) Clethodim exposure induces developmental immunotoxicity and neurobehavioral dysfunction in zebrafish embryos. Fish & shellfish immunology. 86:549-558

Hu, Y.W., Wu, X.M., Ren, S.S., Cao, L., Nie, P., Chang, M.X. (2017) NOD1 deficiency impairs CD44a/Lck as well as PI3K/Akt pathway. Scientific Reports. 7:2979

Oyarbide, U., Iturria, I., Rainieri, S., Pardo, M.A. (2015) Use of Gnotobiotic Zebrafish to Study Vibrio anguillarum Pathogenicity. Zebrafish. 12(1):71-80

Wang, Y.D., Peng, K.C., Wu, J.L., Chen, J.Y. (2014) Transgenic expression of salmon delta-5 and delta-6 desaturase in zebrafish muscle inhibits the growth of Vibrio alginolyticus and affects fish immunomodulatory activity. Fish & shellfish immunology. 39(2):223-30

Hsieh, J.C., Pan, C.Y., and Chen, J.Y. (2010) Tilapia hepcidin (TH)2-3 as a transgene in transgenic fish enhances resistance to Vibrio vulnificus infection and causes variations in immune-related genes after infection by different bacterial species. Fish & shellfish immunology. 29(3):430-439

Peng, K.C., Pan, C.Y., Chou, H.N., and Chen, J.Y. (2010) Using an improved Tol2 transposon system to produce transgenic zebrafish with epinecidin-1 which enhanced resistance to bacterial infection. Fish & shellfish immunology. 28(5-6):905-917

Additional Citations (15):

ZFIN Staff (2023) Curation of NCBI Gene Data Via Shared Ensembl IDs (Supplemental NCBI Load). Automated Data Submission.

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

UniProt curators (2015) Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features.. Automated Data Submission.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

ZFIN Staff (2013) Curation of NCBI Gene Data Via Shared Vega Gene IDs. Automated Data Submission.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.