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Phenotype Figure Summary
Marker:
pomt1
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Karas
et al.
, 2024
Fig. 1
pomt1
sa14667/sa14667
(AB)
head ab2-dag1 labeling absent, abnormal
whole organism Ab1-pomt1 labeling absent, abnormal
Fig. 2
pomt1
sa14667/sa14667
(AB)
anal fin development delayed, abnormal
dorsal fin development delayed, abnormal
whole organism decreased length, abnormal
whole organism viability, abnormal
Fig. 3
pomt1
sa14667/sa14667
(AB)
skeletal muscle cell increased area, abnormal
swimming behavior decreased process quality, abnormal
Fig. 4
pomt1
sa14667/sa14667
(AB)
long double cone cell photoreceptor outer segment disorganized, abnormal
retinal bipolar neuron synapse Ab13-syp labeling decreased distribution, abnormal
retinal bipolar neuron synapse structurally discontinuous, abnormal
retinal cone cell Ab5-gnat2 labeling decreased distribution, abnormal
retinal outer plexiform layer cone cell pedicle retracted, abnormal
retinal outer plexiform layer disorganized, abnormal
retinal rod cell zpr-3 labeling decreased distribution, abnormal
short double cone cell photoreceptor outer segment disorganized, abnormal
short double cone cell zpr-3 labeling decreased distribution, abnormal
Fig. 5
pomt1
sa14667/sa14667
(AB)
whole organism Ab1-pomt1 labeling absent, abnormal
whole organism ab2-dag1 labeling absent, abnormal
whole organism decreased length, abnormal
whole organism viability, abnormal
Fig. 6
pomt1
sa14667/sa14667
(AB)
myotome basement membrane structurally discontinuous, abnormal
skeletal muscle cell decreased length, abnormal
skeletal muscle cell disorganized, abnormal
skeletal muscle cell muscle tendon junction ab1-lama1 labeling decreased distribution, abnormal
skeletal muscle cell muscle tendon junction ab1-lama1 labeling spatial pattern, abnormal
skeletal muscle cell muscle tendon junction structurally discontinuous, abnormal
swimming behavior decreased process quality, abnormal
Fig. 7
pomt1
sa14667/sa14667
(AB)
skeletal muscle cell detached from skeletal muscle cell, abnormal
skeletal muscle cell mitochondrial membrane structurally discontinuous, abnormal
skeletal muscle cell mitochondrion swollen, abnormal
skeletal muscle cell muscle tendon junction structurally discontinuous, abnormal
skeletal muscle cell sarcomere decreased length, abnormal
skeletal muscle cell sarcomere misaligned with skeletal muscle cell sarcomere, abnormal
skeletal muscle cell T-tubule increased size, abnormal
skeletal muscle sarcoplasmic reticulum increased size, abnormal
Fig. 8
pomt1
sa14667/sa14667
(AB)
skeletal muscle cell acetylcholine-gated channel complex decreased amount, abnormal
skeletal muscle cell acetylcholine-gated channel complex decreased distribution, abnormal
skeletal muscle cell neuromuscular junction of skeletal muscle fiber fragmented, abnormal
Fig. 9
pomt1
sa14667/sa14667
(AB)
horizontal cell dendrite structurally discontinuous, abnormal
long double cone cell photoreceptor outer segment disorganized, abnormal
retinal cone cell cone cell pedicle shape, abnormal
retinal ganglion cell axon defasciculated, abnormal
retinal ganglion cell axon zn-8 labeling spatial pattern, abnormal
retinal inner nuclear layer nucleus disorganized, abnormal
retinal outer nuclear layer nucleus disorganized, abnormal
retinal outer plexiform layer Ab13-syp labeling spatial pattern, abnormal
short double cone cell photoreceptor outer segment disorganized, abnormal
Fig. S1
pomt1
sa14667/sa14667
(AB)
skeletal muscle cell sarcoplasmic reticulum Ab1-pomt1 labeling absent, abnormal
Avsar-Ban
et al.
, 2010
Fig. 4
WT + MO1-pomt1
embryo development delayed, abnormal
post-vent region increased curvature, abnormal
somite border curvature, abnormal
swim bladder development disrupted, abnormal
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