Research
Search
Genes / Clones
Expression
Mutants / Tg
Antibodies
Anatomy / GO / Human Disease / Chemical
Publications
Data Mining
Downloads
Data Model
AllianceMine
BioMart
Genomics
BLAST
ZFIN
Ensembl
NCBI
UCSC
Genome Browsers
ZFIN
Ensembl
Vega
GRC
UCSC
NCBI
Resources
Zebrafish Genomics
Other Genome Databases
Resources
General
The Zebrafish Book
Protocol Wiki
Antibody Wiki
Anatomy Atlases
Resources for Students and Educators
Zebrafish Programs
ZF-Health
Husbandry Resources
More...
Resource Centers
Zebrafish International Resource Center (ZIRC)
China Zebrafish Resource Center (CZRC)
European Zebrafish Resource Center (EZRC)
Community
Announcements
News
Meetings
Jobs
Alliance Community Forum
Search
People
Labs
Companies
Societies
International Zebrafish Society (IZFS)
Zebrafish Disease Models Society (ZDMS)
Genetics Society of America (GSA)
Zebrafish Husbandry Association
Support
Nomenclature
Nomenclature Conventions
Line Designations
Wild-Type Lines
Submit a Proposed Gene Name
Submit a Proposed Mutant/Tg Line Name
Publications
Guidelines for Authors
Zebrashare
Citing ZFIN
Using ZFIN
Help & Tips
Glossary
Single Box Search Help
Submit Data
Terms of Use
About Us
About ZFIN
Contact Information
Statistics
Committees
Jobs at ZFIN
Sign In
Phenotype Figure Summary
Marker:
mmachc
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Paz
et al.
, 2023
Fig. 1
mmachc
hg13/hg13
Meckel's cartilage increased distance palatoquadrate cartilage, abnormal
palatoquadrate cartilage increased distance palatoquadrate cartilage, abnormal
Fig. 2
mmachc
hg13/hg13
; zf678Tg
hyosymplectic cartilage chondrocyte disorganized, abnormal
hyosymplectic cartilage nucleus disorganized, abnormal
palatoquadrate cartilage chondrocyte disorganized, abnormal
Fig. 3
mmachc
hg13/hg13
; zf678Tg
hyosymplectic cartilage chondrocyte disorganized, abnormal
hyosymplectic cartilage nucleus disorganized, abnormal
Sloan
et al.
, 2020
Fig. 1
mmachc
hg13/+
(EKW)
, 
mmachc
hg12/hg12
(EKW)
, 
mmachc
hg12/+
(EKW)
, 
mmachc
hg13/hg13
(EKW)
whole organism
mmachc
expression absent, abnormal
whole organism
mmachc
expression decreased amount, abnormal
whole organism dead, abnormal
whole organism decreased life span, abnormal
Fig. 2
mmachc
hg12/hg12
(EKW)
, 
mmachc
hg13/hg13
(EKW)
whole organism 2-methylcitric acid increased amount, abnormal
whole organism decreased height, abnormal
whole organism decreased length, abnormal
whole organism methylmalonic acid increased amount, abnormal
Fig. 3
mmachc
hg13/hg13
(EKW)
whole organism 2-methylcitric acid increased amount, abnormal
whole organism decreased height, abnormal
whole organism decreased length, abnormal
whole organism methylmalonic acid increased amount, abnormal
Fig. 4
mmachc
hg13/hg13
; kj2Tg; w254Tg
, 
mmachc
hg12/hg12
(EKW)
cranial nerve II decreased thickness, abnormal
eye decreased size, abnormal
retinal outer nuclear layer decreased thickness, abnormal
retinal photoreceptor layer decreased thickness, abnormal
retinal rod cell decreased amount, abnormal
Quintana
et al.
, 2014
Fig. 7
WT + MO1-mmachc + MO4-tp53
ceratobranchial cartilage absent, abnormal
ceratohyal cartilage malformed, abnormal
Meckel's cartilage malformed, abnormal
splanchnocranium malformed, abnormal
Your Input Welcome
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Name:
Institution:
Email address:
Please leave blank:
Subject:
Comments:
Send your comments
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.