Genomic Feature
ti262c
- ID
- ZDB-ALT-980203-1165
- Name
- ti262c
- Synonyms
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one point mutation (1)
- Protocol
- adult males treated with ENU
- Lab of Origin
- Nüsslein-Volhard Lab
- Current Source
- European Zebrafish Resource Center (EZRC) ( order this )
- Other Pages
Notes
No data available
Variants
- Variant Type
- Point Mutation
- Variant Location
- Chr 17: 12227705 (GRCz11) (1) Details
- Nucleotide change
- G/A
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- C>T (1)
- Transcript Consequence
- Premature Stop (1)
- Protein Consequence
- Polypeptide Truncation: Arg>Stop (1)
- Flanking Sequence
-
TTCTGTTGGGTCCCGAGTATCAAGATGCTCTGACATCTCAGGCACAGATTCAGAGCTTGGTTCCTGAACAGGAACAACCAACTCTGGTTTAATAACCACATCTATCTTGAGAACCTGAGCCTCTGAAATTCCTTTTAGCTGCTCCTCGCTTACGTTCTCCACAACATCATTGGTAATATTAACACACTCCTCCTCATTTTGGGCTTCCTGTATGCCTAAAGATCTCTCTGCATTGGACAAGTCTCCCCTTGAATTGTCCTTTTCTTTCTCAGGCAGCATAAGAGAAGGCAAGTCCACAGTTGTGTTCCTTTCTACAGGAGCTGTATGTTCCTCAAAAGTGTTTGGAAGTCTTACTGTCACCTCTCGATCCACACTATTGTTTGCTTGCTGCTCTTTCAGAGTAATCAAAAGATCCTCGGGAGCAGGAGCATCATGAAACTCAAGGGTGGTATCGGATTGGTTGGATACAAGACTTGCTTCTTGCCCCAAACTAGGCCGTC
G/A CACGAGAGTGGGAAGCACTTTTGTGGACTCTGCTAAGGGGATTTCTTTAATAGAGGATCCAGTCTCAGATTCTACGTCAGGATTCTCCTGCTCTCCCAGAGAGGGCATGCATGTCATTTTCATATCTACATCTTCCTCTTCAGCATCTGAATGTTCACTCCAGACCCCAATGCTTGCTTTAGCAGGAGGAGAAGATCGCTTAGGAGTATTGTGCTCCCTGTTAACTGAAATCTGTGGAGAACCAAAAGCATTAATCACTCTTGCTAAAATTGTTCCAATGTTTTAATAAGTAGGGCTCATGGAGTATGACTTCTATAATATGCAAGATACAAATTGACAAATGTAAAGGTATATAACTATTTACATTATTATATTTACAGTGATAATAAATGCAATTGATCTGATTTTAGATAGACATTTGATTGTAGAAAAGGCACATTACCCCATTGTTCCAGTGAACAGAGCCTTTGGGAGCTTCTGGAGAATCAGCATCCTCTATG - Additional Sequence
- None
Fish
from 5 publications1 - 10 of 13
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Supplemental Information
- Genotyping protocol
- None
- Morgan, K.J., Doggett, K., Geng, F., Mieruszynski, S., Whitehead, L., Smith, K.A., Hogan, B.M., Simons, C., Baillie, G.J., Molania, R., Papenfuss, A.T., Hall, T.E., Ober, E.A., Stainier, D.Y.R., Gong, Z., Heath, J.K. (2023) ahctf1 and kras mutations combine to amplify oncogenic stress and restrict liver overgrowth in a zebrafish model of hepatocellular carcinoma. eLIFE. 12:
- Cerveny, K.L., Bronstein, H., Hagen, O., Lamb, D.B., Martin, G., Tower, I., Van Duzer, A., Welch, E., Varga, M. (2021) Mutations linked to loss of cell cycle control can render cells responsive to local differentiation cues. microPublication. Biology. 2021:
- Cerveny, K.L., Cavodeassi, F., Turner, K.J., de Jong-Curtain, T.A., Heath, J.K., and Wilson, S.W. (2010) The zebrafish flotte lotte mutant reveals that the local retinal environment promotes the differentiation of proliferating precursors emerging from their stem cell niche. Development (Cambridge, England). 137(13):2107-2115
- de Jong-Curtain, T.A., Parslow, A.C., Trotter, A.J., Hall, N.E., Verkade, H., Tabone, T., Christie, E.L., Crowhurst, M.O., Layton, J.E., Shepherd, I.T., Nixon, S.J., Parton, R.G., Zon, L.I., Stainier, D.Y., Lieschke, G.J., and Heath, J.K. (2009) Abnormal nuclear pore formation triggers apoptosis in the intestinal epithelium of elys-deficient zebrafish. Gastroenterology. 136(3):902-911
- Davuluri, G., Gong, W., Yusuff, S., Lorent, K., Muthumani, M., Dolan, A.C., and Pack, M. (2008) Mutation of the zebrafish nucleoporin elys sensitizes tissue progenitors to replication stress. PLoS Genetics. 4(10):e1000240
- Kazakova, N., Li, H., Mora, A., Jessen, K.R., Mirsky, R., Richardson, W.D., and Smith, H.K. (2006) A screen for mutations in zebrafish that affect myelin gene expression in Schwann cells and oligodendrocytes. Developmental Biology. 297(1):1-13
- Ng, A.N., de Jong-Curtain, T.A., Mawdsley, D.J., White, S.J., Shin, J., Appel, B., Dong, P.D., Stainier, D.Y., and Heath, J.K. (2005) Formation of the digestive system in zebrafish: III. Intestinal epithelium morphogenesis. Developmental Biology. 286(1):114-135
- Wallace, K.N., Akhter, S., Smith, E.M., Lorent, K., and Pack, M. (2005) Intestinal growth and differentiation in zebrafish. Mechanisms of Development. 122(2):157-73
- Yee, N.S., Lorent, K., and Pack, M. (2005) Exocrine pancreas development in zebrafish. Developmental Biology. 284(1):84-101
- Chen, J.N., Haffter, P., Odenthal, J., Vogelsang, E., Brand, M., van Eeden, F.J., Furutani-Seiki, M., Granato, M., Hammerschmidt, M., Heisenberg, C.P., Jiang, Y.J., Kane, D.A., Kelsh, R.N., Mullins, M.C., and Nüsslein-Volhard, C. (1996) Mutations affecting the cardiovascular system and other internal organs in zebrafish. Development (Cambridge, England). 123:293-302
1 - 10 of 12
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