Genomic Feature
rdu60
Notes
No data available
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 7: 12950710 - 12950731 (GRCz11) (1) Details
- Nucleotide change
- AGGCGCAGTGGTATCGCTTCCC/-
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 22 bp deleted in Exon 2 (1)
- Transcript Consequence
- Frameshift, Premature Stop (1)
- Protein Consequence
- Polypeptide Truncation (1)
- Flanking Sequence
-
AGTAGTTTGAACAAGCAGAAAAAAAAGGAAAAGAAAAAAAAATATATATATATATATATATATTTTTTTTTTTTTTTTTTTTCCTAGCCAGCAGTTTTTCCAGCATGTCTGGCTCAATGTCATTAAAATATAAGCAGTGATGTTTCACAATTTTTGGTTTTCCCATAAACAGTTACGCAATACAGGTCTGACCACTTCAGGATTAAATTAGTGTAACTTTCCATAATAAATCTGTTGGGAAAACCCACATCCAGCCCAATCCAAGCCTTATAAATATCTCAGCCTGGATGAAGACATGAACTGAGCGAATCCTGAGTGGTAAGAGATGCTTTCTGTATGCAAGGGAGTGAAGTTACAGAGAGTTCATCAATAGCTGCAGATTTTAGAATTTCTGTGCTGTGATATTAATGTTTGTTTGTTGTAATGTTTGTGTGTGTTCAGTTCTGAAATCATGAAGCTTCTTCTTGCTGTGCTGGTGATGTTTATGGTGGTGGAAGCCC
AGGCGCAGTGGTATCGCTTCCC/- AGGAGAAGCCGCTGGAGGTCAGTTGTTATTCCAGTTTATCTCCATATAGCATGCAAGCACACTCAAAAAAATTACGTTTGTTGTTAGTTCAAACTACATATTTAAAATGAGTTAAAATATCACAATTTGGGACAACTTGATAGTGTTATGTTCAATGTACTTAAATTTTTTAACTCTAATAAATTAATTTAGCATTTTTATCAAATCAATTGTGTGGAACAGTGCATGCAATCTCAAGAAACTGCACTGAAAAAAGTTATTAATTGGATTTACTCACTTGTTTTTTACGGTAAGTGGTTACAAACTATTTATATGGGCTGAATTGCAACAAACAAATTAAGTTGAACATTACTAAGTTAAATTTGTTTGTTTAAAAATTAGCCAACAGTATATAAACTGTTTGCAACCACTTACCTTAAAAAATGTAGTAAATCTGATTATTAATTTTTTTCAGTCTGACTTTTACTGCTTGTTCAAACCACTTATTCAGGGTGTCCGCG - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| saardu60/rdu60 | Homozygous | Unknown | 2 figures  from Murdoch et al., 2019 | 2 figures from Murdoch et al., 2019 | |
| saardu60/rdu60; nz50Tg | Complex | Fig 4 from Murdoch et al., 2019 | |||
| saardu60/rdu60; nz50Tg; rdu64Tg | Complex | Fig 4 from Murdoch et al., 2019 | |||
| saardu60/rdu60; nz50Tg; rdu66Tg | Complex | Fig 4 from Murdoch et al., 2019 | |||
| saardu60/rdu60; nz50Tg; rdu67Tg | Complex | Fig 4 from Murdoch et al., 2019 | |||
| saardu60/rdu60; nz50Tg; rdu68Tg | Complex | Fig 4 from Murdoch et al., 2019 | |||
| saardu60/rdu60; nz117Tg | Complex | 2 figures from Murdoch et al., 2019 | 2 figures from Murdoch et al., 2019 | ||
| saardu60/rdu60; nz117Tg; rdu66Tg | Complex | ||||
| saardu60/rdu60; rdu64Tg | Complex | Fig 4 from Murdoch et al., 2019 | |||
| saardu60/rdu60; rdu66Tg | Complex | Fig 4 from Murdoch et al., 2019 |
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Supplemental Information
- Genotyping protocol
- None
- Yang, L., Jiménez, J.A., Earley, A.M., Hamlin, V., Kwon, V., Dixon, C.T., Shiau, C.E. (2020) Drainage of inflammatory macromolecules from brain to periphery targets the liver for macrophage infiltration. eLIFE. 9:
- Murdoch, C.C., Espenschied, S.T., Matty, M.A., Mueller, O., Tobin, D.M., Rawls, J.F. (2019) Intestinal Serum amyloid A suppresses systemic neutrophil activation and bactericidal activity in response to microbiota colonization. PLoS pathogens. 15:e1007381
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