Genomic Feature
ncv114
- ID
- ZDB-ALT-170522-17
- Name
- ncv114
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one deletion (1)
- Protocol
- embryos treated with
- Lab of Origin
- Mochizuki Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 22: 38049443 - 38049450 (GRCz11) (1) Details
- Nucleotide change
- CCACCAGG/-
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 8 bp deleted in Exon 1 (1)
- Transcript Consequence
- Premature Stop (1)
- Protein Consequence
- None
- Flanking Sequence
-
ATTCTAGACATTTTGTAGGAGACTTCTTCAATGTTGGTATGTTTGAAAAACGTATTCGTCAACTTCCAATGCCGAACATCCATCGTTGCGTTTTGTTTATGAACGAAAGCGTACATAACTGGCTCATTGAATATTCATGAGGGGCTGGAGACGTGATTGAATATTCATAAACTGACAGACAGACACAGGAGCCGCTCAGACTGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGGCTTGAGTTTACAAACTTTCAGAAACTCCGCGATCGGACGCAGGAGGAACAAAAAACTCTCCAAACTCCACGCGGGACAACATGACAAACGCCTTTCTAGCTTTATGACAACTTTTCGACGACTTACAAACACTTTTCAACTCGGCTGAAACTACTTAAGGACGAAAAACAGGAAAAGTTCCTACAGGAATTTTTTTTTCCATCGGCCATTTTAATCGAAGTTTGTTTTGACCATGAGCGGTAATCCTCTCCAGCCGATACCGGG
CCACCAGG/- TGATCCATGTCGCCAAAGACCTGGACACGGATCTGGAGGCTCTTTTTAACTCGGTCATGAACCCGAAACCGAGCTCCTGGAGGAACAAGGATATGCCGCAGTCTTTCTTCCAGGAGCCGGACTCGGGCTCCCACTCCCGGCAGTCCAGCGCGGACTCCGGTTCTCTCCCGCCGAGGGTCCACTTTCGCTCGCGCTCATCTCCGGCGTCCCTACAGCTGCCGGCGGGCTCCGTGAGCGGCCCGAGCCCCGGGAGACTCCACTCCCACACCCGGCACCAGTCCTGCGATGTGGCCGAGGAGCTGCCGCTGCCCCCTGGGTGGGAGATGGCCTTCACCCCCAACGGCCAGAAGTACTTTCTCAAGTAAGAGTTCGTTATTACTGGACATTCCTGCACACTGTTTAGTTCACATTACCAGTTAGTGGAGTGCATACAGTGGGGGGAATGAGTATTGAACACGGTCCTGTTTTGATTTCCTGGGAATAATATTCATAAAGGAGCT - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| wwtr1ncv114/ncv114; ncv12Tg; ncv1Tg; nkuasgfp1aTg | Complex | Fig. 1  from Nakajima et al., 2017 | |||
| wwtr1ncv114/ncv114; yap1ncv117/ncv117 | Complex | 2 figures from Fukui et al., 2018 |
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Supplemental Information
- Genotyping protocol
- None
- Fukui, H., Miyazaki, T., Chow, R.W., Ishikawa, H., Nakajima, H., Vermot, J., Mochizuki, N. (2018) Hippo signaling determines the number of venous pole cells that originate from the anterior lateral plate mesoderm in zebrafish. eLIFE. 7
- Nakajima, H., Yamamoto, K., Agarwala, S., Terai, K., Fukui, H., Fukuhara, S., Ando, K., Miyazaki, T., Yokota, Y., Schmelzer, E., Belting, H.G., Affolter, M., Lecaudey, V., Mochizuki, N. (2017) Flow-Dependent Endothelial YAP Regulation Contributes to Vessel Maintenance. Developmental Cell. 40:523-536.e6
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