Genomic Feature
ug103
- ID
- ZDB-ALT-170119-21
- Name
- ug103
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one deletion (1)
- Protocol
- embryos treated with
- Lab of Origin
- Bertrand Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 4: 6034207 - 6034238 (GRCz11) (1) Details
- Nucleotide change
- GATTGCATGGAGCCAGGCATCATAATGCAAAA/-
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 32 bp deleted in Exon 3 (1)
- Transcript Consequence
- Premature Stop (1)
- Protein Consequence
- Polypeptide Truncation: Asp>Stop (1)
- Flanking Sequence
-
CCATCCACTCCCAGGACAGGCCCTGGGCACGGTGCCCGTCATGCGCAATGGACACATGCCACCCGTGAGTGACAGCAGCACGCCAGGAAGCCCGGTTACCCTGCTAACACTAGCCAACAATCAAGACAGTGAGGTTTGTAAACCCTGCCATCTGCTATCTCTCTCTCTCTCTCTGTGAGTTTGTTCTCATTAATATTCAGATTTGATCACGTCACGTCAGTTTCTCTGATAAGAAGTGCTTCATCCTGACAGTCATGTTTCTGAAATGATGACGCGTCTGTTATTGGATTAGCGCTTTTGTTTATTCACACGACTCTCACTCACTTTTGACACAATGATTGATGAGAGTGAAAATGAAACCCCAAACAAGCAAACAAACATCTCCACTGTTGACGGAGGGCCAAGAGTGAGCTATAATCACTGTTTTCTTTCAGTTTCCGATGGATGAAGTTATTGACGATCTTATTGGCCTTGAAAACGGGTTTAAGGATGGGAGCTTG
GATTGCATGGAGCCAGGCATCATAATGCAAAA/- TAATGTAAGTATAAGCCAAGTTCATGTCTTCAGTGTGTTGACCTGTTGTATGTGCTGTGGCATTATTTAAACCTGTGCACAATGAAAAAGAGATATACTGAGGTTTTATAATTAAAATATACTTGTTTCTGAGTTGACAGAAATACATAATAATTATGAGTATTACATAATAAAGCAAACAACTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTATCATTCTGTCTGTCTGTCTATCATTCTGTTTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATTATTCTGTCTGTCAGTCTGTCTGTCTATCT - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| tfecug103/ug103 | Homozygous | ♀+/- ♂+/- | Fig. 3 from Mahony et al., 2016 | 3 figures  from 2 publications | |
| tfecug103/ug103 | Homozygous | Unknown | 2 figures from Ferrero et al., 2018 |
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Supplemental Information
- Genotyping protocol
- None
- Ferrero, G., Mahony, C.B., Dupuis, E., Yvernogeau, L., Di Ruggiero, E., Miserocchi, M., Caron, M., Robin, C., Traver, D., Bertrand, J.Y., Wittamer, V. (2018) Embryonic Microglia Derive from Primitive Macrophages and Are Replaced by cmyb-Dependent Definitive Microglia in Zebrafish. Cell Reports. 24:130-141
- Mahony, C.B., Pasche, C., Bertrand, J.Y. (2018) Oncostatin M and Kit-Ligand Control Hematopoietic Stem Cell Fate during Zebrafish Embryogenesis. Stem Cell Reports. 10(6):1920-1934
- Mahony, C.B., Fish, R.J., Pasche, C., Bertrand, J.Y. (2016) tfec controls the hematopoietic stem cell vascular niche during zebrafish embryogenesis. Blood. 128(10):1336-45
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